How can I make a friends 25th birthday special?

My best friend since kindergarten is turning 25 in 2 months! I have no problems in the gift department, however I'm trying to think of ways to make this birthday special - either through the decoration of her gifts (ie- if she were turning 21 it could be blackjack themed). I don't know how to make "25" into something special. Any ideas for themes or that 'something extra' that will make her birthday even more special? Thanks so much!